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KMID : 0882420100780020155
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Korean Journal of Medicine
2010 Volume.78 No. 2 p.155 ~ p.162
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Drug therapy of gastroesophageal reflux disease: Good treatment strategies in Korea and recently developed drugs
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Ryu Han-Seung
Choi Suck-Chei
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Abstract
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The prevalence of gastroesophageal reflux disease (GERD) in Western countries ranges between 10% and 20%. Although GERD is increasing in Korea, it is difficult to actively conduct studies due to restrictions in insurance regulations and there are practical limitations to prescribe drugs conforming the evidence-based guidelines. As novel drug therapy for GERD, drugs with new mechanisms that would overcome pharmacokinetic limits of proton pump inhibitors are being investigated. In this review, with regards to drug therapy of GERD, we discuss management strategies suitable for domestic circumstances and drugs that are being newly developed.
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KEYWORD
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Gastroesophageal reflux disease, Drug therapy
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